It seems that the 4th epinephrine auto-injector is available as a GENERIC of the Adrenaclick that is returning to the marketplace. Here lies the confusion: in some states the generics can be replaced by the pharmacist without asking permission. I’ve copied and pasted information from the American Academy of Allergy, Asthma Immunology (AAAAI) and ImmunologyAllergy Asthma Network, Mothers of Asthmatics (AAMA) in regards to understanding this confusing state of 4 epinephrine auto-injectors in the marketplace. These two resources are highly respected leaders in the world of anaphylaxis and asthma and when they speak, I listen. AAMA data below provides links to all four brands available. The solution: make sure when you fill your epinephrine prescriptions that you understand which device you are receiving and that you educate and train yourself on your device.
image courtesy of AAAAI.org
From the AAAAI….
Be Aware of Authorized Generic Epinephrine Autoinjector
It has come to our attention that Lineage Therapeutics, Inc. recently launched an authorized generic version of Adrenaclick® under the name epinephrine injection, USP auto-injector. This product being marketed as a generic epinephrine autoinjector is an “authorized generic” of the Adrenaclick autoinjector only.
We want to make you aware because the availability of this product may result in substitution for other epinephrine autoinjectors at the pharmacy, which could lead to patient and caregiver confusion.
Epinephrine autoinjectors look and function differently from one another, and they have different instructions for use and require different training. You may have trained your patient for the administration of one type of injector, and the pharmacy may provide another type on which the patient has not been trained. During the stress of an anaphylactic reaction, this may be confusing to a patient and could result in the delay or perhaps an error in the administration of the drug.
When having a prescription filled, patients or caregivers should reinforce with the pharmacist the importance of getting the specific epinephrine autoinjector their physician prescribed and that they are trained to use.
You can view each type of epinephrine autoinjector and the instructions for administration at the respective product websites: www.epinephrineautoinject.com, www.adrenaclick.com, www.auvi-q.com and www.epipen.com.
Linda Cox, MD, FAAAAI
Image courtesy of AAMA
From the AAMA…
It has come to our attention that Lineage Therapeutics, Inc. recently launched a generic version of Adrenaclick® under the name epinephrine injection, USP auto-injector. This product, marketed as a generic epinephrine auto-injector, is an “authorized generic” of the Adrenaclick auto-injector only.
The availability of this product could result in substitution for other epinephrine auto-injectors at the pharmacy, leading to confusion.
Epinephrine auto-injectors look and function differently from one another. Each has different instructions for use and requires different training. You may be trained on one type of auto-injector, and the pharmacy may provide another for which you were not trained to use.
During the stress of an anaphylactic reaction, this could result in a delay or perhaps an error in the administration of the drug. Time is of the essence during an anaphylactic reaction. Make sure you are well prepared with the proper prescribed medication. No surprises!
When having a prescription filled, patients or caregivers should reinforce with the pharmacist the importance of getting the specific epinephrine auto-injector their physician prescribed and that they are trained to use. Be sure to check the bag before leaving the pharmacy drive-through or counter. Accept no substitutes!
View each type of epinephrine auto-injector and the instructions for administration at the respective product web sites:
Visit www.aanma.org for more information on the signs and symptoms of anaphylaxis, as well as how to ensure you are prepared in the event of an emergency.
Allergy & Asthma Network
Mothers of Asthmatics
8201 Greensboro Dr., Suite 300
McLean, VA 22102
Fax: 703.288.4003 | www.aanma.org
Image courtesy of digitalart via Freedigitalphotos.net
Hopefully these two pieces of data help clears up the confusion. The bottom line goes directly back to the hard fact that we will always need to train everyone within our world regarding how to respond to an emergency and that we always carry two epinephrine auto-injectors.